Histopathology (Mastectomy) examination is offered by Molecular Diagnostics, an advanced and NABL & NABH-accredited diagnostic Centre. This type of test requires analysis of breast tissue taken during a mastectomy to examine it under a microscope. It aids doctors in detecting abnormal tissue changes, assisting them to determine if a tumour is cancerous or whether a patient is cancer-free, and assessing the crucial characteristics of the cancerous tumours of the breast.
What is Histopathology (Mastectomy)?
Histopathology is a microscopic examination of tissues to detect changes due to disease. During a mastectomy examination, the tissue that is removed during the procedure is examined thoroughly to determine the structure and nature of the cells. The specimen is then fixed, processed, embedded, cut, and stained before it is viewed under the microscope. The pathologist looks at the tissue to see if any cells are growing abnormally, if there is a tumour and its features, and to see other changes that may occur. Slightly more sections or special investigations could be necessary, depending on the specimen and clinical information.
Common Reasons for Histopathology (Mastectomy)
Breast Cancer Evaluation: This involves the evaluation of tissue they have taken out from the breast as part of the surgery to establish whether or not cancer is confirmed and the type of cancer.
Tumour Assessment: Assessment of the size, grade, and other microscopic properties of the tumour.
Surgical Margin Examination: The examination of the margins of tissue removed to determine if any cancer cells are present.
Lymph Node Evaluation: Examining lymph nodes found in the surgery where the test is performed to determine if any contain cancer.
Abnormal Breast Tissue Changes: Looking for other abnormal changes in the breast tissue once it has been taken out.
Treatment Planning: Giving results that can assist doctors in their planning of any future treatment and follow-up.
Conditions Evaluated
Benign and Malignant Breast Conditions
Microscopic examination helps identify non-cancerous and cancerous changes in breast tissue. It supports the final diagnosis based on the features observed in the specimen.
Breast Tumour Characteristics
The examination helps assess the type, size, and grade of a tumour. These findings provide important information about the characteristics of the tumour.
Surgical Margin Involvement
The pathologist examines the edges of the removed breast tissue to determine whether abnormal or cancerous cells are present at the surgical margins.
Lymph Node Involvement
If lymph nodes are submitted along with the mastectomy specimen, they are examined for the presence of cancer cells. This information may help doctors assess the extent of the disease.
Other Tissue Abnormalities
The examination may also identify inflammatory changes, tissue degeneration, and other microscopic abnormalities in the breast specimen.
Why Choose Molecular Diagnostics and Therapy?
Molecular Diagnostics and Therapy is a state-of-the-art diagnostic facility based on the integration of radiology, nuclear medicine, and pathology diagnostics. The key elements of our pathology services are the careful handling of specimens, the regular and accurate processing in the lab, meticulous microscopic examination, and detailed reporting. We strive to achieve consistent quality and deliver patient care in keeping with our goals and objectives, while also giving reliable diagnostic support.
Book Your Histopathology (Mastectomy)
If you've been recommended to do Histopathology (Mastectomy), please contact Molecular Diagnostics and Therapy to send the specimen for examination. The following should be provided: doctor's prescription, clinical notes are relevant, previous biopsy or histopathology report, and other medical records are available. Specimen(s) of a mastectomy must be sent with all appropriate surgical and clinical information for appropriate processing and examination.
Test information: No fasting required. A mastectomy tissue specimen is required for examination.
Reporting: As per the centre's reporting schedule.
Fasting is not required for the histopathology examination.
The mastectomy tissue specimen must be collected and submitted by the treating hospital or surgical team.
Ensure the specimen is placed in the appropriate container with the recommended preservative, usually formalin, as per laboratory instructions.
Provide the doctor's prescription, surgery details, clinical notes, and relevant medical history.
Submit previous biopsy or histopathology reports, if available.
Include details of the surgical procedure, tumour location, and lymph nodes removed, if applicable.
Ensure the specimen container is properly labelled with the patient's details and specimen information.
Follow the laboratory's instructions for specimen handling, storage, and transportation.
हिस्टोपैथोलॉजी जाँच के लिए खाली पेट रहने की आवश्यकता नहीं होती है।
मास्टेक्टॉमी के दौरान निकाले गए टिश्यू सैंपल को इलाज करने वाले अस्पताल या सर्जिकल टीम द्वारा ही जमा करवाया जाना चाहिए।
सैंपल को लैब के निर्देशों के अनुसार उचित कंटेनर में रखें। आमतौर पर इसके लिए फॉर्मेलिन प्रिजर्वेटिव का उपयोग किया जाता है।
डॉक्टर की पर्ची, सर्जरी से संबंधित जानकारी, क्लिनिकल नोट्स और मेडिकल हिस्ट्री साथ दें।
पिछली बायोप्सी या हिस्टोपैथोलॉजी रिपोर्ट उपलब्ध हों, तो जमा करें।
सर्जरी की जानकारी, ट्यूमर की जगह और यदि लिम्फ नोड्स निकाले गए हैं, तो उनका विवरण भी दें।
सैंपल के कंटेनर पर मरीज की जानकारी और सैंपल का विवरण सही तरीके से लिखा होना चाहिए।
सैंपल को सुरक्षित रखने और लैब तक पहुंचाने के लिए लैब के निर्देशों का पालन करें।
The breast tissue specimen removed during the mastectomy is collected by the surgical team and sent to the histopathology laboratory.
The specimen is received, labelled, and checked along with the relevant clinical and surgical details.
The pathologist examines the specimen macroscopically, noting its size, appearance, tumour location, and other relevant features.
Representative tissue sections are selected for microscopic examination, including the tumour, surrounding breast tissue, and surgical margins.
Lymph nodes are also examined if they are submitted with the specimen.
The selected tissue sections undergo fixation, processing, and embedding in paraffin wax.
Thin tissue sections are prepared and stained, usually with Haematoxylin and Eosin (H&E).
The pathologist examines the slides to assess the tumour type, size, grade, surgical margins, lymph node involvement, and other relevant tissue changes.
Additional tests, such as immunohistochemistry, may be recommended when required.
A detailed histopathology report is prepared to support further treatment planning and clinical management.
* For details, please see service-related policies
Disclaimer: The information provided on this page is for educational and informational purposes only.
It is not intended to replace professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional for advice regarding your individual health condition or treatment.