Visit Molecular Diagnostics and Therapy, a diagnostic centre which is NABL & NABH Accredited in treating thyroid-related cancer with Iodine - 131 (I-131) Therapy. This is a high dose of radioiodine that will target the thyroid tissue and iodine-avid thyroid cancer cells. With some patients with differentiated thyroid cancer, a treatment dose of 200 m Ci can be indicated based on the individual clinical judgment and treatment plan of the Nuclear Medicine specialist.
About Iodine-131 Therapy – 200 mCi
Iodine-131 therapy is a specialized/unique nuclear medicine treatment that is relatively utilized in an individual with differentiated thyroid cancer, most commonly papillary and follicular thyroid cancer. Iodine is needed by the thyroid cells to make thyroid hormones. Radioactive iodine (I-131) takes advantage of this property by directing specifically targeted radiation to the cancer cells and the thyroid tissue that have that ability. Therapeutic activity of 200mci can be considered for selected cases based on previous course of therapy, risk categorization, and previous therapy response. Treatment each person receives is individualized to that person by their treatment provider.
What is Iodine-131 Therapy?
Iodine-131 is a radioactive isotope of iodine which releases beta and gamma radiation. Once inside the body, it is taken up by cells within the thyroid that avidly take up iodine. The beta radiation kills the intended thyroid tissue and the cancers, while the gamma radiation provides radioactive products for imaging and monitoring. This will typically be administered orally in the form of a capsule or liquid, dosed and supervised in an appropriate healthcare facility. Iodine-131 therapy may be administered following thyroid surgery to kill any non-removed thyroid tissue, for some remaining thyroid tissue, and/or to control iodine-avid metastatic disease in thyroid cancer.
Common Reasons for Iodine-131 Therapy – 200 mCi
Differentiated Thyroid Cancer: To treat some papillary and follicular thyroid cancers which are iodine-receptive.
Post-Surgical Ablation: If there is any tissue left in the thyroid gland after the thyroidectomy, then it will be treated as necessary.
For metastatic (cancer that has spread beyond the thyroid) thyroid cancer, treated with iodine that has been targeted for specific deposits in the body.
Recurrent Thyroid Cancer: Evaluate and treat the appropriate recurrent thyroid cancer patients with iodine.
High-risk thyroid cancer: To provide increased therapy to a selected cohort of patients, depending on tumour type and clinical risk.
Conditions Evaluated and Treated
Follicular Thyroid Carcinoma
Follicular thyroid carcinoma cells may retain iodine uptake after thyroidectomy. The ability to take up iodine depends on tumour biology and differentiation, not on preserving iodine uptake during surgery.
Residual Thyroid Tissue
There may be any amount of normal thyroid tissue remaining if you've undergone surgery for your thyroid. Radioiodine treatment may kill this tissue and aid the management and subsequent monitoring of the disease.
Iodine-Avid Metastatic Disease
Differentiated thyroid cancer can spread to regional lymph nodes and distant organs, particularly the lungs and bones. I-131 treatment can be used to help focus on areas if there is uptake of iodine in the cancer deposits.
Persistent or Recurrent Differentiated Thyroid Cancer
If investigations have shown persistent or recurrent iodine-avid disease and the patient is likely to benefit from further treatment, then radioiodine therapy may be considered.
Why Choose Molecular Diagnostics and Therapy?
A trusted Centre (NABL and NABH accredited) in Nuclear Medicine, Radiology and Pathology, Molecular Diagnostics and Therapy. Our focus in the services of Nuclear Medicine is on the correct selection of patients for nuclear medicine treatment, individualization of treatment plans for patients, minimization of radiation exposure to patients, and clinical supervision. We provide a treatment sequence that is organized, safe, and effective, with follow-up.
Book Your Iodine-131 Therapy – 200 mCi.
If your doctor has suggested having Iodine-131 Therapy with 200mCi for thyroid cancer, please call Molecular Diagnostics and Therapy to schedule a consultation and therapy. Present the histopathology report, records from thyroid surgery if applicable, previous thyroid radioiodine treatment details, thyroglobulin reports, thyroid function tests, images, and prescription of the treating physician for thyroid treatment. Treatment will be deemed appropriate following specialist assessment and established suitability, and then scheduled thereafter.
Test information: Fasting NOT needed
Reporting: Within 24 hours*
Fasting is not required unless specifically advised by the Nuclear Medicine specialist.
Bring your treating doctor's prescription, histopathology report, thyroid surgery records, and details of any previous Iodine-131 treatment.
Carry recent thyroglobulin reports, thyroid function test results, and relevant imaging reports or scans.
Inform the specialist about your current medicines, supplements, allergies, and any previous medical conditions.
Follow the specialist's instructions regarding thyroid hormone medication and any preparation required before treatment. Do not stop or change medicines on your own.
Inform the specialist if you are pregnant, planning pregnancy, or breastfeeding. Iodine-131 therapy is contraindicated during pregnancy and breastfeeding.
Follow the centre's instructions regarding a low-iodine diet, if prescribed before treatment.
Discuss radiation-safety precautions and any arrangements needed at home after treatment with the Nuclear Medicine team.
जब तक न्यूक्लियर मेडिसिन विशेषज्ञ विशेष रूप से न कहें, तब तक खाली पेट रहने की आवश्यकता नहीं है।
डॉक्टर की पर्ची, बायोप्सी या हिस्टोपैथोलॉजी रिपोर्ट, थायरॉइड सर्जरी से जुड़े रिकॉर्ड और पहले हुए Iodine-131 उपचार की जानकारी साथ लाएँ।
थायरोग्लोबुलिन रिपोर्ट, थायरॉइड फंक्शन टेस्ट और संबंधित स्कैन या इमेजिंग रिपोर्ट भी साथ रखें।
अपनी वर्तमान दवाओं, सप्लीमेंट्स, एलर्जी और पुरानी बीमारियों की जानकारी विशेषज्ञ को दें।
थायरॉइड की दवाओं और उपचार से पहले की तैयारी के बारे में विशेषज्ञ के निर्देशों का पालन करें। अपनी ओर से कोई दवा बंद न करें या उसमें बदलाव न करें।
यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो विशेषज्ञ को अवश्य बताएँ। गर्भावस्था और स्तनपान के दौरान Iodine-131 उपचार नहीं किया जाता।
यदि विशेषज्ञ कम आयोडीन वाले आहार की सलाह दें, तो उपचार से पहले दिए गए निर्देशों का पालन करें।
उपचार के बाद घर पर बरती जाने वाली विकिरण-सुरक्षा सावधानियों और आवश्यक व्यवस्थाओं के बारे में न्यूक्लियर मेडिसिन टीम से जानकारी लें।
The Nuclear Medicine specialist will review your medical history, histopathology findings, thyroid surgery records, previous Iodine-131 treatment details, blood test results, and relevant imaging.
Your suitability for the 200 mCi therapeutic dose will be assessed individually based on the type and stage of thyroid cancer, iodine uptake, previous treatment response, and overall clinical condition.
Before administration, the team will explain the treatment process, expected precautions, and radiation-safety instructions.
The prescribed Iodine-131 dose is generally administered orally in the form of a capsule or liquid under specialist supervision.
After administration, the radioactive iodine is absorbed by iodine-avid thyroid tissue and cancer cells, where it delivers targeted radiation.
Depending on the prescribed dose and radiation-safety requirements, you may need to remain in a designated isolation room for a period determined by the treating team.
The specialist will provide instructions regarding hydration, personal hygiene, contact with other people, and other radiation-safety precautions after treatment.
Follow-up appointments and investigations will be advised to assess treatment response and guide further management.
* For details, please see service-related policies
Disclaimer: The information provided on this page is for educational and informational purposes only.
It is not intended to replace professional medical advice, diagnosis, or treatment.
Always consult a qualified healthcare professional for advice regarding your individual health condition or treatment.