Low-Dose CT Scan for Lung Cancer Screening

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01 Aug, 2025

Dr. Nikunj Jain

Dr. Nikunj Jain

Co-Founder and HOD - Nuclear Medicine ,

MBBS, DRM, DNB, FEBNM, FANMB, Dip. CBNC

Lung cancer remains one of the leading causes of cancer-related deaths worldwide, largely because it is often diagnosed at an advanced stage. Early detection plays a crucial role in improving survival rates. One of the most promising tools for this is the Low-Dose CT scan (LDCT), which can detect lung cancer before symptoms appear. Unlike a standard CT, LDCT uses significantly less radiation, making it safer for routine screening among high-risk individuals. In cities like Delhi NCR and across India, awareness of LDCT is growing, encouraging more people to opt for timely screening.

Low-Dose CT (LDCT) Scan

A Low-Dose CT scan is a specialized form of computed tomography designed to use lower doses of radiation compared to a standard chest CT scan. It creates detailed cross-sectional images of the lungs, allowing radiologists to detect small nodules or masses that may suggest early-stage lung cancer.

Key features:

  • Uses about 75–90% less radiation than standard CT scans.
  • Non-invasive and painless procedure.
  • Takes only a few minutes to complete.

By combining safety with accuracy, LDCT offers an effective method to detect lung cancer early, when treatment options are more effective and survival rates are higher.

Why is LDCT important for lung cancer screening?

Most lung cancers develop silently, with symptoms like persistent cough or chest pain often appearing only in advanced stages. At that point, treatment becomes more challenging, and survival rates drop. LDCT screening addresses this gap by:

  • Detecting small, early-stage tumors that might be missed on a chest X-ray.
  • Improving chances of successful treatment.
  • Reducing mortality from lung cancer among high-risk individuals.

Multiple large studies, including the National Lung Screening Trial (NLST) in the US, have shown that LDCT screening can reduce lung cancer deaths by about 20% in people at high risk.

Who should consider an LDCT scan for lung cancer screening?

LDCT screening isn’t recommended for everyone. It is most beneficial for individuals at higher risk, including:

  • Adults aged 50 to 80 years.
  • Those with a significant smoking history (typically 20–30 pack-years).
  • Current smokers or those who quit within the past 15 years.
  • Individuals with a family history of lung cancer.
  • People exposed to occupational risks such as asbestos.

It’s always best to discuss personal risk factors with a healthcare provider to determine if LDCT is appropriate.

How is the LDCT scan performed?

The LDCT procedure is simple, quick, and usually does not require special preparation:

  • You may be asked to wear a hospital gown and remove any metal objects.
  • You will lie on a motorized table that slides into the CT scanner.
  • During the scan, you will need to hold your breath briefly (around 5–10 seconds) to avoid blurring the images.
  • The scanner takes multiple images of your chest, which are later compiled into detailed views of your lungs.
  • The entire process generally takes less than 10 minutes.

Since the radiation dose is lower than a standard CT scan, the test can be safely repeated annually for those at continued risk.

Advantages of LDCT screening

LDCT has emerged as an essential tool in preventive healthcare for high-risk groups. Some key benefits include:

  • Early detection: Identifies small lung nodules that may indicate early cancer.
  • Reduced mortality: Proven to decrease lung cancer deaths in high-risk populations.
  • Non-invasive: Quick and painless, with no need for injections or dyes in routine screening.
  • Lower radiation exposure: Safer for repeated annual scans.
  • Improved treatment options: Detecting cancer early often allows for less aggressive and more effective treatment.

Limitations and risks

While LDCT is highly beneficial, it is important to understand its limitations:

  • False positives: Sometimes, nodules that are benign may appear suspicious, leading to further tests or biopsies.
  • Radiation exposure: Though minimal, there is still some exposure.
  • Overdiagnosis: Some detected cancers may be slow-growing and may never cause harm, but their discovery can lead to anxiety and unnecessary treatment.
  • Cost and availability: While increasingly common in cities like Delhi NCR, access to LDCT may still be limited in smaller towns.

Discussing these risks with a healthcare provider helps patients make an informed decision about screening.

What happens if something abnormal is found?

If the LDCT scan detects a nodule or abnormal area, the next steps usually include:

  • Comparing the scan to any previous images to assess growth.
  • Scheduling follow-up scans to monitor changes over time.
  • Conducting further diagnostic tests such as:
    • PET-CT scans for detailed imaging.
    • Biopsy to confirm if the nodule is cancerous.
  • Referral to a lung specialist or oncologist if needed.

Many small nodules turn out to be harmless; regular follow-up is key to distinguishing benign from malignant findings.

LDCT vs. chest X-ray

Historically, chest X-rays were used for lung screening but proved ineffective in reducing deaths from lung cancer. LDCT has clear advantages:

  • Detects much smaller nodules.
  • Provides detailed cross-sectional views of the lungs.
  • Proven to lower lung cancer mortality in high-risk groups.

As a result, LDCT is now the recommended standard for lung cancer screening in eligible individuals.

When not to choose LDCT

LDCT is generally not recommended for:

  • Individuals below 50 or above 80 years with no other risk factors.
  • Those who have quit smoking over 15 years ago and remain symptom-free.
  • People with significant health conditions that limit life expectancy or ability to undergo potential treatment.

For these groups, the risks of screening may outweigh the benefits.

LDCT availability and cost in India

In India, especially in metro cities like Delhi, Mumbai, and Bengaluru, LDCT scans are now offered by many leading hospitals and diagnostic centers. The cost typically ranges from ₹4,000 to ₹10,000 depending on the center and technology used.

Annual screening costs should be weighed against the potential benefit of early detection, which can save lives and reduce the need for more expensive treatments later.

Tips for those planning an LDCT scan

  • Consult your doctor first to assess if you meet the high-risk criteria.
  • Choose an accredited diagnostic center with experienced radiologists.
  • Share your smoking history and any prior scans with your doctor.
  • Discuss the possible results and follow-up plans in advance.
  • Stay consistent with annual scans if recommended.

Conclusion

Low-Dose CT scan for lung cancer screening has revolutionized the approach to early detection among high-risk populations. By offering detailed imaging with much less radiation, LDCT makes it possible to identify cancer before symptoms appear, when treatment outcomes are often better. While it is not for everyone, for smokers and those with a family history, it can be life-saving. As awareness and availability grow in India, especially in cities like Delhi NCR, more people can benefit from this powerful tool against lung cancer.

Frequently Asked Questions (FAQ’s)

What is a Low-Dose CT scan?

A Low-Dose CT scan uses reduced radiation to create detailed images of the lungs, mainly for screening high-risk individuals.

Who should get an LDCT scan?

Adults aged 50–80 with a significant smoking history or other risk factors should consider annual screening.

Is LDCT painful?

No, it is a non-invasive and painless procedure.

Does LDCT completely prevent lung cancer?

No, but it helps detect cancer early, improving the chances of successful treatment.

How often should LDCT be done?

Typically once a year, as long as the person remains at high risk.

What happens if the scan shows a nodule?

Your doctor may order follow-up scans, PET-CT, or a biopsy to determine if it is cancerous.

Does LDCT involve contrast dye?

Routine LDCT screening usually does not require contrast.

What is the radiation dose compared to standard CT?

LDCT uses about 75–90% less radiation.

Is LDCT available in India?

Yes, especially in major cities like Delhi, Mumbai, and Bengaluru.

Can non-smokers get LDCT?

It is usually recommended only for those at higher risk, but a doctor can advise based on individual history.

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