Arthritis: Causes, Symptoms, Types & Tests

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28 Jul, 2025

Dr. Nikunj Jain

Dr. Nikunj Jain

Co-Founder and HOD - Nuclear Medicine ,

MBBS, DRM, DNB, FEBNM, FANMB, Dip. CBNC

Arthritis is one of the most common yet often misunderstood health conditions worldwide. It refers to inflammation of one or more joints, leading to pain, stiffness, swelling, and reduced range of motion. While arthritis is frequently associated with older adults, it can affect people of all ages, including children. The disease can be mild, causing occasional discomfort, or severe enough to interfere with daily life and mobility. Early diagnosis, understanding the different types, and proper treatment can significantly improve quality of life for those living with arthritis.

Arthritis

Arthritis is not a single disease but rather an umbrella term for over 100 different types of joint disorders. The most common characteristic shared by these conditions is joint inflammation, which can lead to cartilage damage, joint deformity, and disability if left untreated.

Arthritis can be broadly divided into two main categories:

  • Inflammatory arthritis: Includes autoimmune types like rheumatoid arthritis, where the immune system attacks the joints.
  • Non-inflammatory or degenerative arthritis: Primarily includes osteoarthritis, where cartilage gradually wears away over time.

The impact of arthritis goes beyond physical discomfort—it can also lead to emotional distress, reduced work capacity, and limitations in daily activities.

Causes of Arthritis

The causes of arthritis vary depending on the specific type, but several risk factors and triggers are commonly recognized:

Common causes include:

  • Age: Risk increases with age, especially for osteoarthritis.
  • Genetics: Family history can increase susceptibility to conditions like rheumatoid arthritis.
  • Joint injury: Previous injuries can lead to post-traumatic arthritis years later.
  • Obesity: Excess weight places extra stress on joints, particularly hips and knees.
  • Autoimmune response: In some types, such as rheumatoid arthritis, the immune system mistakenly attacks joint tissues.
  • Infections: Certain bacterial or viral infections can trigger reactive arthritis.
  • Metabolic conditions: Diseases like gout result from uric acid crystal build-up in joints.

Symptoms of Arthritis

Arthritis symptoms can range from mild discomfort to severe pain and disability. The most common symptoms include:

  • Joint pain: May be dull, aching, or sharp, and often worsens with movement.
  • Stiffness: Especially noticeable in the morning or after periods of inactivity.
  • Swelling: Caused by inflammation and fluid accumulation around the joint.
  • Reduced range of motion: Difficulty bending, straightening, or rotating affected joints.
  • Warmth and redness: Joints may feel warm to the touch or appear red.
  • Fatigue: Common in inflammatory types like rheumatoid arthritis.
  • Joint deformity: Advanced arthritis can lead to visible changes in joint shape.

Types of Arthritis

Over 100 types of arthritis have been identified, but here are some of the most common:

1. Osteoarthritis (OA)

  • The most common form.
  • Caused by cartilage wear and tear over time.
  • Often affects weight-bearing joints like knees, hips, and spine.

2. Rheumatoid Arthritis (RA)

  • An autoimmune disorder where the immune system attacks joint linings.
  • Can affect multiple joints and lead to joint deformity.
  • More common in women than men.

3. Gout

  • Results from uric acid crystal deposits in joints.
  • Often affects the big toe but can occur in other joints.
  • Characterized by sudden, severe pain and swelling.

4. Psoriatic Arthritis

  • Develops in some people with the skin condition psoriasis.
  • Can cause joint pain, swelling, and skin changes.

5. Ankylosing Spondylitis

  • Primarily affects the spine, leading to stiffness and potential fusion of vertebrae.
  • More common in men.

6. Juvenile Arthritis

  • Affects children and teenagers.
  • Symptoms similar to adult arthritis, but onset is before age 16.

Tests Used to Detect Arthritis

Diagnosing arthritis involves a combination of clinical evaluation and diagnostic tests:

  • Physical examination: Checks for swelling, tenderness, range of motion, and warmth around joints.
  • Blood tests: Identify markers of inflammation (like ESR and CRP) and specific antibodies (such as rheumatoid factor or anti-CCP) for autoimmune arthritis.
  • Imaging tests:
    • X-rays: Detect joint space narrowing, bone changes, and osteophytes.
    • MRI and ultrasound: Provide detailed images of soft tissues, cartilage, and inflammation.
  • Joint fluid analysis: Helps identify infection, crystals (gout), or signs of inflammation.
  • Bone scan: Detects subtle joint changes not visible on standard X-rays.

Timely testing helps determine the type of arthritis, its severity, and the most appropriate treatment plan.

Conclusion

Arthritis is a widespread condition that affects millions worldwide, impacting daily life and mobility. It comes in many forms, from age-related osteoarthritis to autoimmune diseases like rheumatoid arthritis. Early detection, understanding the underlying causes, and following treatment plans can help manage symptoms and slow disease progression. Lifestyle adjustments—such as maintaining a healthy weight, exercising regularly, and protecting joints from injury—play an essential role in arthritis prevention and management. While arthritis can’t always be cured, its impact can be significantly reduced, allowing people to lead active, fulfilling lives.

Frequently Asked Questions (FAQs)

1. What is arthritis?
Arthritis is the inflammation of joints, leading to pain, stiffness, and swelling.

2. Can arthritis be cured?
While most types cannot be completely cured, symptoms can be managed effectively with treatment.

3. What is the most common type of arthritis?
Osteoarthritis, caused by cartilage wear and tear, is the most common type.

4. Is arthritis only for older people?
No, arthritis can affect people of all ages, including children and young adults.

5. What tests help diagnose arthritis?
X-rays, MRI, blood tests, and joint fluid analysis are commonly used.

6. Does diet affect arthritis?
A balanced diet can help reduce inflammation and manage weight, easing pressure on joints.

7. Can exercise help arthritis?
Yes, gentle exercise helps maintain joint flexibility and reduce stiffness.

8. What are early signs of arthritis?
Morning stiffness, joint pain, mild swelling, and reduced range of motion.

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