Brain Tumor: Causes, Symptoms, Types & Tests

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28 Jul, 2025

Dr. Nikunj Jain

Dr. Nikunj Jain

Co-Founder and HOD - Nuclear Medicine ,

MBBS, DRM, DNB, FEBNM, FANMB, Dip. CBNC

Brain Tumor: Causes, Symptoms, Types & Tests

A brain tumor is a serious health condition that can affect anyone, regardless of age or gender. It occurs when abnormal cells grow in or around the brain, sometimes leading to pressure on brain tissues and affecting essential functions like memory, balance, vision, or speech. Brain tumors can be benign (non-cancerous) or malignant (cancerous), and while some grow slowly and remain localized, others spread quickly and may impact life expectancy. Early detection, accurate diagnosis, and treatment can significantly improve quality of life and outcomes.

Brain Tumor

A brain tumor is defined as an abnormal growth of cells within the brain or the central spinal canal. Tumors can arise from brain tissue itself (primary tumors) or spread to the brain from cancers elsewhere in the body (secondary or metastatic tumors). Brain tumors vary in size, location, growth rate, and potential impact on brain function. Some may remain unnoticed for years, while others cause severe symptoms rapidly.

Causes of Brain Tumor

While the exact cause of many brain tumors remains unknown, several factors may contribute to their development:

  • Genetic mutations: Changes in DNA can lead to uncontrolled cell growth.
  • Family history: Rare genetic conditions like neurofibromatosis or Li-Fraumeni syndrome increase risk.
  • Radiation exposure: High doses of ionizing radiation, like previous radiation therapy to the head.
  • Weakened immune system: Conditions like HIV/AIDS or long-term immunosuppressive treatment.
  • Age: Brain tumors can occur at any age, but certain types are more common in children or older adults.
  • Environmental and occupational exposure: Contact with certain chemicals, although the evidence is limited.

While lifestyle factors like smoking or diet are linked to other cancers, they haven’t been strongly linked to brain tumors.

Symptoms of Brain Tumor

Symptoms of brain tumors can vary depending on the tumor’s size, type, and location, but common signs include:

  • Persistent headaches: Often worse in the morning or when lying down.
  • Seizures: New onset of seizures without prior history.
  • Nausea and vomiting: Especially if persistent and unexplained.
  • Cognitive changes: Memory problems, confusion, or difficulty concentrating.
  • Vision or hearing problems: Blurred vision, double vision, or hearing loss.
  • Weakness or numbness: Usually on one side of the body.
  • Balance and coordination issues: Trouble walking or frequent falls.
  • Speech difficulties: Trouble speaking or understanding words.
  • Personality or behavior changes: Increased irritability or mood swings.

These symptoms do not always indicate a brain tumor but should prompt medical evaluation if persistent.

Types of Brain Tumor

Brain tumors can be classified by origin (primary vs. secondary) and by whether they are benign or malignant:

1. Primary brain tumors: Originate in brain tissues.

  • Gliomas: Develop from glial cells (e.g., astrocytomas, oligodendrogliomas, glioblastomas).
  • Meningiomas: Arise from the meninges (protective layers of the brain).
  • Pituitary adenomas: Begin in the pituitary gland.
  • Schwannomas: Develop from nerve sheath cells.
  • Medulloblastomas: Common in children; fast-growing tumors.

2. Secondary (metastatic) brain tumors: Spread to the brain from cancers elsewhere, like lung, breast, kidney, or melanoma.

Benign vs. malignant:

  • Benign tumors: Non-cancerous, usually slower-growing, but can still cause problems due to location.
  • Malignant tumors: Cancerous, can grow rapidly and spread to nearby tissues.

Tests Used to Detect Brain Tumor

Diagnosing a brain tumor involves multiple tests to determine its type, location, and impact:

  • Neurological exam: Checks vision, balance, coordination, and reflexes.
  • Imaging tests:
    • MRI (Magnetic Resonance Imaging): Most common, detailed images of brain structures.
    • CT scan (Computed Tomography): Quick scan often used initially, especially in emergencies.
  • Biopsy: Removal of a tissue sample to confirm diagnosis and tumor type.
  • MRS (Magnetic Resonance Spectroscopy): Analyzes chemical composition of the tumor.
  • PET scan (Positron Emission Tomography): Helps assess tumor metabolism and spread.
  • Lumbar puncture: Examines cerebrospinal fluid for cancer cells (in some cases).

Early and accurate testing helps doctors choose the best treatment plan.

Conclusion

A brain tumor is more than just a medical term; it represents a condition that can deeply affect daily life, cognitive abilities, and emotional health. Though the causes aren’t always clear, genetic factors, radiation exposure, and certain medical conditions play a role. Recognizing early symptoms such as persistent headaches, vision changes, or new seizures can lead to earlier diagnosis and treatment. With advancements in imaging, surgery, radiation, and targeted therapies, many patients with brain tumors now experience better outcomes than in the past. Awareness, timely medical consultation, and individualized treatment plans remain the key to managing this complex disease effectively.

Frequently Asked Questions (FAQ’s)

1. What is a brain tumor?
A brain tumor is an abnormal growth of cells in or around the brain.

2. Are all brain tumors cancerous?
No, brain tumors can be benign (non-cancerous) or malignant (cancerous).

3. What causes a brain tumor?
The exact cause is often unknown, but genetics and radiation exposure may increase risk.

4. What are the early signs of a brain tumor?
Persistent headaches, vision changes, nausea, seizures, and personality changes.

5. How is a brain tumor diagnosed?
Usually through MRI, CT scans, and sometimes biopsy.

6. Can brain tumors be treated?
Yes, treatment may include surgery, radiation, chemotherapy, or targeted therapies.

7. Are children at risk of brain tumors?
Yes, some types like medulloblastomas are more common in children.

8. What is the survival rate for brain tumors?
It varies widely depending on type, size, location, and overall health.

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