PET vs CT Scan: Differences, Uses

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05 Jul, 2025

Dr. Nikunj Jain

Dr. Nikunj Jain

Co-Founder and HOD - Nuclear Medicine ,

MBBS, DRM, DNB, FEBNM, FANMB, Dip. CBNC

PET scan (Positron Emission Tomography) and CT scan (Computed Tomography) are two major diagnostic imaging techniques widely used in modern medicine to identify abnormalities and health conditions within the body. These imaging tests help detect issues ranging from tumors to organ function, guiding effective treatment decisions. While both scans are highly useful, they serve slightly different purposes. A CT scan primarily provides structural details of internal organs using X-rays, whereas a PET scan goes a step further by evaluating the functional and metabolic activity of tissues with the help of a radioactive tracer. This makes PET scans more effective in detecting diseases like cancer at a cellular level before structural changes become visible on other scans.

What is a PET Scan?

PET stands for Positron Emission Tomography. It is a highly advanced imaging technique used to evaluate the function of tissues and organs at the cellular level. This scan works by introducing a small amount of radioactive tracer—commonly Fluorodeoxyglucose (FDG) or Iodine-131—into the patient’s body. The tracer travels through the bloodstream and accumulates in areas with high metabolic activity, such as cancer cells.

A PET scan is particularly useful for:

  • Identifying cancer and checking how far it has spread (staging)
  • Monitoring the effectiveness of cancer treatment
  • Evaluating brain disorders like epilepsy or Alzheimer’s disease
  • Assessing heart function and blood flow

Before undergoing a PET scan, patients are often required to take a serum creatinine test to ensure kidney function is normal, as the radioactive tracer is processed through the kidneys. Though rare, allergic reactions to the tracer can occur, making prior consultation essential.

What is a CT Scan?

CT stands for Computed Tomography. This imaging procedure uses X-rays combined with computer technology to create cross-sectional (3D) images of the body. It offers a detailed view of bones, organs, soft tissues, and blood vessels, enabling physicians to identify structural abnormalities.

CT scans are commonly used to:

  • Detect internal injuries or bleeding
  • Locate tumors, cysts, and abscesses
  • Guide surgical procedures or biopsies
  • Examine bone fractures or joint problems
  • Monitor the progress of diseases

The scan is quick, generally painless, and widely available. Sometimes, contrast dye (either orally or intravenously) is administered to enhance image clarity, especially when scanning soft tissues or blood vessels.

PET Scan vs CT Scan: A Comparative Table

 

PET Scan (Positron Emission Tomography) CT Scan (Computed Tomography)
Typically 2–3 hours (including tracer uptake time) 10–30 minutes
Generally more expensive due to radiotracer and complexity Less expensive than PET scans
Often combined with CT for PET-CT scans for better accuracy Can be performed alone or combined with PET or MRI
Available in specialized centers Widely available in most hospitals and diagnostic centers
Shows metabolic and functional activity of tissues Provides detailed anatomical images of structures
Functional imaging Structural imaging
Uses radioactive tracers (e.g., FDG, I-131, etc.) Uses iodinated contrast dye (optional)
Moderate to high (from radiotracer and scanner) Moderate (from X-rays)
Detecting cancer, brain disorders, heart diseases Diagnosing fractures, tumors, internal bleeding
Lower anatomical detail but shows cellular activity High-resolution images of organs, bones, and tissues

What is the Cost of a PET scan in Delhi NCR?

The cost of a PET scan varies depending on several factors such as the healthcare facility, city, and the specific area being scanned. In Delhi NCR, the average price of a PET scan typically ranges between INR 12,000 to INR 45,000. The use of radioactive tracers, specialized equipment, and extended scan time contribute to its higher cost. Patient can visit Molecular Diagnostic and Therapy Centre for affordable and quality tests results or click here to book appointment.

What is the Cost of a CT scan in Delhi NCR?

CT scans are generally more affordable than PET scans and are commonly available in most diagnostic centers. In Delhi NCR, the average cost of a CT scan lies between INR 1,500 to INR 12,000, depending on the type of scan (e.g., brain, chest, abdomen) and whether contrast dye is used.

Conclusion

Both PET and CT scans are vital tools in medical diagnostics. While CT scans offer clear images of structural abnormalities such as bone fractures, tumors, or infections, PET scans provide valuable insight into metabolic processes and cellular function. For conditions like cancer, combining both PET and CT scans offers a comprehensive view—helping in early diagnosis, staging, and monitoring of treatment response. Choosing between a PET or CT scan depends on the symptoms, diagnosis required, and your doctor’s evaluation. With the advancement of medical imaging technology, these scans have significantly improved the ability of healthcare providers to detect and treat diseases more effectively and at earlier stages, improving patient outcomes and survival rates.

 

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